You Can Spot Dementia 9 Years Before A Diagnosis — Here’s How

June 10, 2023

Early intervention can make a world of difference in slowing the progression of cognitive decline in neurodegenerative diseases like dementia. Unfortunately, early signs of dementia can be elusive—especially in sporadic dementia changes. You see, changes in brain structure and neuroimaging can be detectable 10 to 25 years before symptom onset of genetic dementia patients (i.e., those with a gene mutation linked to dementia risk). 

Sporadic dementia cases aren’t as easy to assess, but a 2022 Alzheimer’s & Dementia review outlines eight early signs of dementia that can become apparent up to nine years before a medical diagnosis.

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In the review, researchers analyzed data from the U.K. Biobank cohort study, which follows 50,000 individuals of the general population between the ages of 40 and 69, to look for early manifestations of neurodegenerative diseases—including Alzheimer’s disease, frontotemporal dementia, and Lewy body dementia (aka dementia with Lewy bodies). 

They found several early signs of cognitive and functional changes common in these three types of dementia. It’s worth noting that these pre-diagnostic signs were strongest in Alzheimer’s patients but detected in frontotemporal and Lewy body dementia patients as well. 

Catching these signs can initiate early intervention in sporadic dementia cases, helping to slow the progression of these debilitating diseases.

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1. Fluid intelligence: The ability to solve problems in a creative way using logic and reason worsens (e.g., completing puzzles, solving a murder mystery, finding another way home when your regular route is blocked).

2. Reaction time: Response to a stimulant slows down (e.g., reacting to oncoming traffic, burning food, or an incoming phone call).

3. Numeric memory: The ability to use working memory to hold and calculate numbers worsens (e.g., ingredient measurements, simple math equations).

4. Prospective memory: The ability to recall information worsens (e.g., forgetting where you left your keys, doctor appointments, or a recent event).

5. Visual memory: The ability to recall visual information worsens (e.g., a familiar face like your neighbor’s or place like your local grocery store).

(Note: These pre-diagnostic impairments in day-to-day functions were only found in Alzheimer’s disease patients.)

6. Increased number of falls

7. Decreased grip strength

8. Increased tendency toward weight loss

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• Smoke cigarettes
• Overindulge in alcoholic beverages